Protective Role of Folic Acid in Oxidative Stress Induced by Methionine over Load on Lipids and Lipoproteins Levels in Female New Zealand Rabbits

Ruqaih Kareem Mohammed AL- kenany 1, Saad H.Abd-Altaif 2 and Wefak Gaborry Al-Bazii 3
1 Department of Clinical Laboratories, College of Applied Medical Sciences, University of Karbala, Karbala, Iraq.
2 Department of Biology, College of Pure sciences Education, University of Karbala, Karbala, Iraq.
3 College of Veterinary Medicine, University of Karbala, Karbala, Iraq.

ABSTRACT Objectives: The aim of this study was examine to know protective role of folic acid in oxidation stress that results by over load of methionine. Methods: In these study used 18 female of New Zealand rabbits . the working including measuring the TC,TG,HDL,LDL and VLDL levels in blood after intubated over load of methionine and compered with control. Results: The results show that a significant decrease (p<0.05) in HDL levels and a significant increase (p<0.05) in TC, TG, LDL and VLDL in G2 compared with G1 and G3. Conclusion: From the results of the present study , we can be concluded that methionine overload state effects on lipids and lipoproteins and folic acid have protective role in oxidative stress that resulted by over load methionine.