Role of Hormone Irisin in Induce Metabolic Syndrome

 

Hayder B. Abbas Al-Ghreaty 1 , Ruqaih Kareem Mohammed ALkenany 2 and Mohammed S. Mohammed 1
1 Directorate of Education in Karbala, Ministry of Education, Iraq.
2 Clinical Laboratories Department, Applied Medical Sciences College, Karbala University, Iraq.

ABSTRACT

Objective: The aim of this study was examine to know effect of Irisin hormone on MetS patients. Methods: These contain Monograph 124 patients metabolic. The working criteria developed by the NCEP: ATPIII that included blood pressure, body mass index, fasting glucose. In addition to measuring the levels of the Irisin, The data collected included age, BMI and duration of disease. Results: Results show that significant decrease(p<0.05) in serum levels Irisin hormone in MetS with infected diabetic patients compared between MetS is not infected diabetic patients in both sexes, Also showed in compared between male in two group and female too The results show that significant decrease(p<0.01) in serum levels Irisin hormone in MetS with infected diabetic patients compared between metabolic syndrome is not infected diabetic patients in both sexes, The results showed significant decrease in Irisin level accord age especially in(44-54) year group. No change significantly in hormone level accord duration of disease and body mass index group. The results display that blood pressure and BMI there is no change significantly between MetS patients (diabetic and non-diabetic) but all these parameter. Conclusion: Low level of serum Irisin hormone obtained in this study suggested that clinical trials should be undertaken to assess the impact of reduce serum Irisin hormone as biomarker predictor the MetS that leads to risk factor in diabetic type-II patients.